The workshop is a joint initiative supported by the Reference Site Collaborative Network (RSCN), SCIROCCO Exchange, VIGOUR, SHAFE/NET4Age-Friendly and ProMIS communities. It builds on products delivered by those projects and communities, and aims to support further scaling-up of previously EU-funded initiatives. The workshop will provide an overview of the current framework for regional health and care innovative ecosystems to addrerss a life-course approach to active and healthy ageing focusing on key learning outcomes and priority topics from involved communities, including interactive and case-based scenarios.